Real time 3D ultrasound imaging

Sanofi Pasteur, Canada’s largest vaccination company is about to launch the new whooping cough immunization vaccine for workplace and home protection - Adacel. It is scheduled to go out to general use in May. Adacel goes alongside with Sanofi Pasteur’s newest workplace flu shot. It will provide guaranteed protection to Canadians during cold and frosty northern winters.

Sanofi Pasteur is a true innovator in the sphere of Canadian medical treatment. Its innovative bladder cancer treatment medicines and handy travel diarrhea remedies shook the whole pharma market last year. All in all, during the last two years Sanofi Pasteur has extended its line of previously purely vaccination products targeted against dozens of preventable diseases such as influenza, polio, meningitis, diphtheria, tetanus, acellular Pertussis and more.

Sanofi Pasteur was originally founded as the preventable diseases vaccination business of the Sanofi-Aventis Group, the third largest pharmaceutical company in the world.

Canadian Health Ministry official - Michael Mitchell - revealed a new national immunization strategy. Yesterday on Canadian television he stated that both houses of Parliament are reviewing the National Immunization Strategy (NIS) initiative, which is focused mainly on making Meningitis and Hepatitis A vaccination obligatory in all Canadian public and private schools.

The NIS has assisted the vaccination program planning in Canada since 2003, being based on the idea that all issues connected with immunization must be on the forefront of the Canadian public health agenda. This initiative is also backed and lobbied by Canada’s largest vaccination company, the developers of various well-known immunization shots like Vivaxim, Adacel, Menactra or Immucyst- Sanofi Pasteur.

Latest Toronto Star’s articles assess the probability of NIS to be endorsed as “reasonably high”. Political reviewers expect the initiative to be approved in the first reading, having no exact financing figures for it specified. The National Immunization Strategy initiative will be discussed in Ottawa in the beginning of May. If approved, it may go in effect in September 2008, just with the new schoolyear.

Major depression, the kind of depression that will most likely benefit from treatment with medications, is more than just “the blues.” It is a condition that lasts 2 weeks or more, and interferes with a person’s ability to carry on daily tasks and enjoy activities that previously brought pleasure. Depression is associated with abnormal functioning of the brain. An interaction between genetic tendency and life history appears to determine a person’s chance of becoming depressed. Episodes of depression may be triggered by stress, difficult life events, side effects of medications, or medication/substance withdrawal, or even viral infections that can affect the brain.

Depressed people will seem sad, or “down,” or may be unable to enjoy their normal activities. They may have no appetite and lose weight (although some people eat more and gain weight when depressed). They may sleep too much or too little, have difficulty going to sleep, sleep restlessly, or awaken very early in the morning. They may speak of feeling guilty, worthless, or hopeless; they may lack energy or be jumpy and agitated. They may think about killing themselves and may even make a suicide attempt. Some depressed people have delusions (false, fixed ideas) about poverty, sickness, or sinfulness that are related to their depression. Often feelings of depression are worse at a particular time of day, for instance, every morning or every evening.

Not everyone who is depressed has all these symptoms, but everyone who is depressed has at least some of them, co-existing, on most days. Depression can range in intensity from mild to severe. Depression can co-occur with other medical disorders such as cancer, heart disease, stroke, Parkinson’s disease, Alzheimer’s disease, and diabetes. In such cases, the depression is often overlooked and is not treated. If the depression is recognized and treated, a person’s quality of life can be greatly improved.

Antidepressants are used most often for serious depressions, but they can also be helpful for some milder depressions. Antidepressants are not “uppers” or stimulants, but rather take away or reduce the symptoms of depression and help depressed people feel the way they did before they became depressed.

The doctor chooses an antidepressant based on the individual’s symptoms. Some people notice improvement in the first couple of weeks; but usually the medication must be taken regularly for at least 6 weeks and, in some cases, as many as 8 weeks before the full therapeutic effect occurs. If there is little or no change in symptoms after 6 or 8 weeks, the doctor may prescribe a different medication or add a second medication such as lithium, to augment the action of the original antidepressant. Because there is no way of knowing beforehand which medication will be effective, the doctor may have to prescribe first one and then another. To give a medication time to be effective and to prevent a relapse of the depression once the patient is responding to an antidepressant, the medication should be continued for 6 to 12 months, or in some cases longer, carefully following the doctor’s instructions. When a patient and the doctor feel that medication can be discontinued, withdrawal should be discussed as to how best to taper off the medication gradually. Never discontinue medication without talking to the doctor about it. For those who have had several bouts of depression, long-term treatment with medication is the most effective means of preventing more episodes.

Dosage of antidepressants varies, depending on the type of drug and the person’s body chemistry, age, and, sometimes, body weight. Traditionally, antidepressant dosages are started low and raised gradually over time until the desired effect is reached without the appearance of troublesome side effects. Newer antidepressants may be started at or near therapeutic doses.

Early Antidepressants. From the 1960s through the 1980s, tricyclic antidepressants (named for their chemical structure) were the first line of treatment for major depression. Most of these medications affected two chemical neurotransmitters, norepinephrine and serotonin. Though the tricyclics are as effective in treating depression as the newer antidepressants, their side effects are usually more unpleasant; thus, today tricyclics such as imipramine, amitriptyline, nortriptyline, and desipramine are used as a second- or third-line treatment. Other antidepressants introduced during this period were monoamine oxidase inhibitors (MAOIs). MAOIs are effective for some people with major depression who do not respond to other antidepressants. They are also effective for the treatment of panic disorder and bipolar depression. MAOIs approved for the treatment of depression are phenelzine (Nardil), tranylcypromine (Parnate), and isocarboxazid (Marplan). Because substances in certain foods, beverages, and medications can cause dangerous interactions when combined with MAOIs, people on these agents must adhere to dietary restrictions. This has deterred many clinicians and patients from using these effective medications, which are in fact quite safe when used as directed.

The past decade has seen the introduction of many new antidepressants that work as well as the older ones but have fewer side effects. Some of these medications primarily affect one neurotransmitter, serotonin, and are called >selective serotonin reuptake inhibitors (SSRIs). These include fluoxetine (Prozac), sertraline (Zoloft), fluvoxamine (Luvox), paroxetine (Paxil), and citalopram (Celexa).

The late 1990s ushered in new medications that, like the tricyclics, affect both norepinephrine and serotonin but have fewer side effects. These new medications include venlafaxine (Effexor) and nefazadone (Serzone).

Cases of life-threatening hepatic failure have been reported in patients treated with nefazodone (Serzone). Patients should call the doctor if the following symptoms of liver dysfunction occur—yellowing of the skin or white of eyes, unusually dark urine, loss of appetite that lasts for several days, nausea, or abdominal pain.

Other newer medications chemically unrelated to the other antidepressants are the sedating mirtazepine (Remeron) and the more activating bupropion (Wellbutrin). Wellbutrin has not been associated with weight gain or sexual dysfunction but is not used for people with, or at risk for, a seizure disorder.

Read the rest of this entry »

Also called: Candidiasis, Moniliasis

Candida is the scientific name for yeast. It is a fungus that lives almost everywhere, including in your body. Usually, your immune system keeps yeast under control. If you are sick or taking antibiotics, it can multiply and cause an infection.Yeast infections affect different parts of the body in different ways:

• Thrush is a yeast infection that causes white patches in your mouth
• Esophagitis is thrush that spreads to your esophagus, the tube that takes food from your mouth to your stomach. Esophagitis can make it hard or painful to swallow
• Women can get vaginal yeast infections, causing itchiness, pain and discharge
• Yeast infections of the skin cause itching and rashes
• Yeast infections in your bloodstream can be life-threatening

Antifungal medicines eliminate yeast infections in most people. If you have a weak immune system, treatment might be more difficult.
You can cure yeast infections through natural cure as describe by Sarah Summer in her popular ebook Sarah Summer Natural Cure for Yeast Infection

Everyone experiences anxiety at one time or another — “butterflies in the stomach” before giving a speech or sweaty palms during a job interview are common symptoms. Other symptoms include irritability, uneasiness, jumpiness, feelings of apprehension, rapid or irregular heartbeat, stomachache, nausea, faintness, and breathing problems.

Anxiety is often manageable and mild, but sometimes it can present serious problems. A high level or prolonged state of anxiety can make the activities of daily life difficult or impossible. People may have generalized anxiety disorder (GAD) or more specific anxiety disorders such as panic, phobias, obsessive-compulsive disorder (OCD), or post-traumatic stress disorder (PTSD).

Both antidepressants and antianxiety medications are used to treat anxiety disorders. The broad-spectrum activity of most antidepressants provides effectiveness in anxiety disorders as well as depression. The first medication specifically approved for use in the treatment of OCD was the tricyclic antidepressant clomipramine (Anafranil). The SSRIs, fluoxetine (Prozac), fluvoxamine (Luvox), paroxetine (Paxil), and sertraline (Zoloft) have now been approved for use with OCD. Paroxetine has also been approved for social anxiety disorder (social phobia), GAD, and panic disorder; and sertraline is approved for panic disorder and PTSD. Venlafaxine (Effexor) has been approved for GAD.

Antianxiety medications include the benzodiazepines, which can relieve symptoms within a short time. They have relatively few side effects: drowsiness and loss of coordination are most common; fatigue and mental slowing or confusion can also occur. These effects make it dangerous for people taking benzodiazepines to drive or operate some machinery. Other side effects are rare.

Benzodiazepines vary in duration of action in different people; they may be taken two or three times a day, sometimes only once a day, or just on an “as-needed” basis. Dosage is generally started at a low level and gradually raised until symptoms are diminished or removed. The dosage will vary a great deal depending on the symptoms and the individual’s body chemistry.

It is wise to abstain from alcohol when taking benzodiazepines, because the interaction between benzodiazepines and alcohol can lead to serious and possibly life-threatening complications. It is also important to tell the doctor about other medications being taken.

People taking benzodiazepines for weeks or months may develop tolerance for and dependence on these drugs. Abuse and withdrawal reactions are also possible. For these reasons, the medications are generally prescribed for brief periods of time—days or weeks—and sometimes just for stressful situations or anxiety attacks. However, some patients may need long-term treatment.

It is essential to talk with the doctor before discontinuing a benzodiazepine. A withdrawal reaction may occur if the treatment is stopped abruptly. Symptoms may include anxiety, shakiness, headache, dizziness, sleeplessness, loss of appetite, or in extreme cases, seizures. A withdrawal reaction may be mistaken for a return of the anxiety because many of the symptoms are similar. After a person has taken benzodiazepines for an extended period, the dosage is gradually reduced before it is stopped completely. Commonly used benzodiazepines include clonazepam (Klonopin), alprazolam (Xanax), diazepam (Valium), and lorazepam (Ativan).

The only medication specifically for anxiety disorders other than the benzodiazepines is buspirone (BuSpar). Unlike the benzodiazepines, buspirone must be taken consistently for at least 2 weeks to achieve an antianxiety effect and therefore cannot be used on an “as-needed” basis.

Beta blockers, medications often used to treat heart conditions and high blood pressure, are sometimes used to control “performance anxiety” when the individual must face a specific stressful situation—a speech, a presentation in class, or an important meeting. Propranolol (Inderal, Inderide) is a commonly used beta blocker.

A family-centered program that improves parent-child dynamics and family functioning is more effective at discouraging Hispanic youth from engaging in risky behavior than programs that target specific behaviors, according to a study published in the December 2007 issue of the Journal of Consulting and Clinical Psychology.

Hispanic adolescents are at higher risk for substance abuse and risky sexual behavior than other ethnic groups, according to the U.S. Centers for Disease Control and Prevention. And while they represent 14 percent of the U.S. population, they account for a disproportionate 18 percent of all HIV/AIDS cases in the nation.¹

Several types of interventions exist that aim to reduce or prevent risky behavior like substance use and unsafe sexual behavior among non-Hispanic white youth, but no studies have been conducted to determine the relative effectiveness of similar programs targeted to Hispanic youth. Guillermo Prado, Ph.D., of the University of Miami, and colleagues randomly assigned 266 eighth-grade Hispanic youth and their primary caregivers (usually the mother) to one of three interventions:

• Familias Unidas plus Parent-Preadolescent Training for HIV Prevention (PATH)
• English for Speakers of Other Languages (ESOL) plus PATH
• ESOL plus HeartPower for Hispanics, an American Heart Association program

Familias Unidas plus PATH was designed to promote positive adolescent development by increasing parental involvement and teaching more effective parental communication techniques. The program was designed to be more consistent with Hispanic cultural expectations, in which life is family-centered and vital to an individual’s emotional support. PATH is designed to specifically increase parent-adolescent communication about sexual behavior and HIV risks, but it does not target family dynamics specifically. HeartPower for Hispanics is designed to encourage healthier behaviors among Hispanic youth to reduce obesity and heart disease risks.

The interventions were conducted over one year, and researchers followed up with participants at one and two years after the intervention ended. They found that the Familias Unidas plus PATH intervention was much more effective than the other two interventions in reducing cigarette use, and moderately more effective in reducing illicit drug use and unsafe sexual behavior among the adolescents.

“It is noteworthy that Familias Unidas + PATH produced favorable outcomes among the youth, even though most sessions in this group were conducted only with the parents.” said Dr. Prado. “The findings also suggest that targeting specific health behaviors such as cigarette smoking and risky sexual behavior within the context of strengthening the family may be the most effective approach for Hispanic adolescents.”

Read the rest of this entry »

Children, the elderly, and pregnant and nursing women have special concerns and needs when taking psychotherapeutic medications. Some effects of medications on the growing body, the aging body, and the childbearing body are known, but much remains to be learned. Research in these areas is ongoing.

In general, the information throughout this booklet applies to these groups, but the following are a few special points to keep in mind.

Children

The 1999 MECA Study (Methodology for Epidemiology of Mental Disorders in Children and Adolescents) estimated that almost 21 percent of U.S. children ages 9 to 17 had a diagnosable mental or addictive disorder that caused at least some impairment. When diagnostic criteria were limited to significant functional impairment, the estimate dropped to 11 percent, for a total of 4 million children who suffer from a psychiatric disorder that limits their ability to function.⁶

It is easy to overlook the seriousness of childhood mental disorders. In children, these disorders may present symptoms that are different from or less clear-cut than the same disorders in adults. Younger children, especially, and sometimes older children as well, may not talk about what is bothering them. For this reason, it is important to have a doctor, another mental health professional, or a psychiatric team examine the child.

Many treatments are available to help these children. The treatments include both medications and psychotherapy—behavioral therapy, treatment of impaired social skills, parental and family therapy, and group therapy. The therapy used is based on the child’s diagnosis and individual needs.

When the decision is reached that a child should take medication, active monitoring by all caretakers (parents, teachers, and others who have charge of the child) is essential. Children should be watched and questioned for side effects because many children, especially younger ones, do not volunteer information. They should also be monitored to see that they are actually taking the medication and taking the proper dosage on the correct schedule.

Childhood-onset depression and anxiety are increasingly recognized and treated. However, the best-known and most-treated childhood-onset mental disorder is attention deficit hyperactivity disorder (ADHD). Children with ADHD exhibit symptoms such as short attention span, excessive motor activity, and impulsivity which interfere with their ability to function especially at school. The medications most commonly prescribed for ADHD are called stimulants. These include methylphenidate (Ritalin, Metadate, Concerta), amphetamine (Adderall), dextroamphetamine (Dexedrine, Dextrostat), and pemoline (Cylert). Because of its potential for serious side effects on the liver, pemoline is not ordinarily used as a first-line therapy for ADHD. Some antidepressants such as bupropion (Wellbutrin) are often used as alternative medications for ADHD for children who do not respond to or tolerate stimulants.

Based on clinical experience and medication knowledge, a physician may prescribe to young children a medication that has been approved by the FDA for use in adults or older children. This use of the medication is called “off-label.” Most medications prescribed for childhood mental disorders, including many of the newer medications that are proving helpful, are prescribed off-label because only a few of them have been systematically studied for safety and efficacy in children. Medications that have not undergone such testing are dispensed with the statement that “safety and efficacy have not been established in pediatric patients.” The FDA has been urging that products be appropriately studied in children and has offered incentives to drug manufacturers to carry out such testing. The National Institutes of Health and the FDA are examining the issue of medication research in children and are developing new research approaches.

The use of the other medications described in this booklet is more limited with children than with adults. Therefore, a special list of medications for children, with the ages approved for their use, appears immediately after the general list of medications. Also listed are NIMH publications with more information on the treatment of both children and adults with mental disorders.

The Elderly

Persons over the age of 65 make up almost 13 percent of the population of the United States, but they receive 30 percent of prescriptions filled. The elderly generally have more medical problems, and many of them are taking medications for more than one of these conditions. In addition, they tend to be more sensitive to medications. Even healthy older people eliminate some medications from the body more slowly than younger persons and therefore require a lower or less frequent dosage to maintain an effective level of medication.

The elderly are also more likely to take too much of a medication accidentally because they forget that they have taken a dose and take another one. The use of a 7-day pill-box, as described earlier in this brochure, can be especially helpful for an elderly person.

The elderly and those close to them—friends, relatives, caretakers—need to pay special attention and watch for adverse (negative) physical and psychological responses to medication. Because they often take more medications—not only those prescribed but also over-the-counter preparations and home, folk, or herbal remedies—the possibility of adverse drug interactions is high.

Women during the Childbearing Years

Because there is a risk of birth defects with some psychotropic medications during early pregnancy, a woman who is taking such medication and wishes to become pregnant should discuss her plans with her doctor. In general, it is desirable to minimize or avoid the use of medication during early pregnancy. If a woman on medication discovers that she is pregnant, she should contact her doctor immediately. She and the doctor can decide how best to handle her therapy during and following the pregnancy. Some precautions that should be taken are:⁷

• If possible, lithium should be discontinued during the first trimester (first 3 months of pregnancy) because of an increased risk of birth defects.
• If the patient has been taking an anticonvulsant such as carbamazepine (Tegretol) or valproic acid (Depakote)—both of which have a somewhat higher risk than lithium—an alternate treatment should be used if at all possible. The risks of two other anticonvulsants, lamotrigine (Lamictal) and gabapentin (Neurontin) are unknown. An alternative medication for any of the anticonvulsants might be a conventional antipsychotic or an antidepressant, usually an SSRI. If essential to the patient’s health, an anticonvulsant should be given at the lowest dose possible. It is especially important when taking an anticonvulsant to take a recommended dosage of folic acid during the first trimester.
• Benzodiazepines are not recommended during the first trimester.

The decision to use a psychotropic medication should be made only after a careful discussion between the woman, her partner, and her doctor about the risks and benefits to her and the baby. If, after discussion, they agree it best to continue medication, the lowest effective dosage should be used, or the medication can be changed. For a woman with an anxiety disorder, a change from a benzodiazepine to an antidepressant might be considered. Cognitive-behavioral therapy may be beneficial in helping an anxious or depressed person to lower medication requirements. For women with severe mood disorders, a course of electroconvulsive therapy (ECT) is sometimes recommended during pregnancy as a means of minimizing exposure to riskier treatments.

After the baby is born, there are other considerations. Women with bipolar disorder are at particularly high risk for a postpartum episode. If they have stopped medication during pregnancy, they may want to resume their medication just prior to delivery or shortly thereafter. They will also need to be especially careful to maintain their normal sleep-wake cycle. Women who have histories of depression should be checked for recurrent depression or postpartum depression during the months after the birth of a child.

Women who are planning to breastfeed should be aware that small amounts of medication pass into the breast milk. In some cases, steps can be taken to reduce the exposure of the nursing infant to the mother’s medication, for instance, by timing doses to post-feeding sleep periods. The potential benefits and risks of breastfeeding by a woman taking psychotropic medication should be discussed and carefully weighed by the patient and her physician.

A woman who is taking birth control pills should be sure that her doctor knows this. The estrogen in these pills may affect the breakdown of medications by the body—for example, increasing side effects of some antianxiety medications or reducing their ability to relieve symptoms of anxiety. Also, some medications, including carbamazepine and some antibiotics, and an herbal supplement, St. John’s wort, can cause an oral contraceptive to be ineffective.

Why understanding yeast infections is so important:

For most men and women, a yeast infection is an irritation, but it isn’t life-threatening, but there are times when it is not safe to treat your symptoms by yourself.

For instance, if your immune system has been compromised because of an illness or medical treatment, Candida albicans yeast can be your worst nightmare, and must be treated immediately by a physician.

If you are pregnant or nursing a child, it is especially important to get a professional diagnosis. Some yeast infection signs can also be symptoms of bacterial infections, which can cause permanent damage if they aren’t treated. And some over-the-counter medications may not be safe for your baby.

Read the rest of this entry »

We live in a society that focuses on appearance. Beautiful and skinny people are accorded an elevated and lofty standing. Because of the importance placed on beauty and weight, many people are willing to sacrifice their health to realize a goal of thinness and perfection. The impact of these misplaced priorities has been substantial. People that do not meet the accepted standards for attractiveness suffer. Jobs may be lost to applicants perceived as more attractive. Dating is more challenging. Even friendships can be harder to develop. This can often result in poor body image and low self esteem. Consequently, many people take drastic efforts to conform more closely to the accepted level of attractiveness. Plastic surgery and expensive skin procedures have become acceptable and sometimes expected. Health is disregarded and has become an acceptable sacrifice in the pursuit of beauty. Even though the risks are well-known and the cost substantial, the number of people that are undergoing these chancy procedures are staggering. People, especially women, are willing to accept the costs, financial and otherwise. But is it really worth it? Diet and exercise is not the easiest route to pursue. You do have to sacrifice time, energy, effort, and yes even some of your favorite foods. But, unlike plastic surgery, the results are always worth the cost. What you get out of it far outweighs what you have to put in to it. Eating right and exercising will keep your body functioning properly and the results will be reflected in your appearance. Your skin will look healthy. Your metabolism will increase. And the results will persist as long as you do.

The majority of Hurricane Katrina survivors who developed mental disorders after the disaster are not receiving the mental health services they need, and many who were receiving mental health care prior to the hurricane were not able to continue with treatment, according to an NIMH-funded study published online ahead of print December 17, 2007, in the American Journal of Psychiatry.

Philip Wang, M.D., Dr.P.H., formerly of Harvard University, and now director of the NIMH Division of Services and Intervention Research, and colleagues conducted telephone surveys in early 2006 with 1,043 adults who had been affected by the hurricane in Alabama, Mississippi and the New Orleans metropolitan area. Respondents were asked if they had a diagnosed mental disorder, such as depression or anxiety, prior to the hurricane for which they received professional treatment. Those who did not have a pre-existing disorder were asked if they had developed and been treated for a mental disorder since the hurricane struck. Treatment included medication and/or psychotherapy from mental health professionals, general medical providers, religious or spiritual advisors, or complementary and alternative medicine professionals.

Nineteen percent of people surveyed said they had developed a mental disorder after the hurricane. Among them, only 18.5 percent were receiving any treatment. Among the 21 percent of respondents who said they had been in treatment for a mental disorder prior to the hurricane, 23 percent were having difficulty maintaining treatment after the storm, and were receiving reduced treatment or no treatment at all.

Respondents with pre-hurricane mental disorders cited loss of financial resources, such as unemployment and loss of insurance, as a significant barrier to maintaining treatment. In addition, they noted that many mental health care facilities and personnel were lost after the hurricane, especially in the New Orleans area. Those who were identified as having a post-hurricane mental disorder commonly indicated they felt no need to seek treatment. The majority of the respondents who did get treatment after the hurricane received it from general medical providers. Many of these respondents received medication, but few had access to psychotherapy.

The researchers note that their study sample likely underrepresented those who were most disadvantaged or ill because people unreachable by phone were excluded. Wang and colleagues conclude that future disaster management plans should anticipate the mental health care needs of people with pre-existing disorders who need to maintain treatment, as well as survivors who may be vulnerable to emotional difficulties and mental disorders triggered by the disaster itself.

Read the rest of this entry »